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Brand Names: Uroxatral

Generic Name: alfuzosin (Pronunciation: al FUE zoe sin)

What is alfuzosin (Uroxatral)?

Alfuzosin is in a group of drugs called alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Alfuzosin relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Alfuzosin is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Alfuzosin may also be used for other purposes not listed in this medication guide.

round, yellow, imprinted with APO, ALF 10

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What are the possible side effects of alfuzosin (Uroxatral)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, uroxatral tongue, or throat.

Stop using alfuzosin and call your doctor at once if you have a serious side effect such as:

  • new or worsening chest pain;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • feeling like you might pass out; or
  • penis erection that is painful or lasts 4 hours or longer.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about alfuzosin (Uroxatral)?

You should not use alfuzosin if you are allergic to it, if you have severe liver disease, or if you are also using ketoconazole (Nizoral), itraconazole (Sporanox), or ritonavir (Norvir). Do not take alfuzosin with other similar medicines such as doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin).

Alfuzosin may cause dizziness or fainting. Be careful if you drive or do anything that requires you to be alert. Avoid standing for long periods of time or becoming overheated during exercise and in hot weather. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Alfuzosin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using alfuzosin before surgery unless your surgeon tells you to.

There are many other drugs that can interact with alfuzosin. Tell your doctor about all medications you use.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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